DIVINE SAVINGSFree Shipping on Orders $300+
All products are intended for laboratory research purposes only. Not for human consumption.

ALPHA AMINOS

Signal precedes structure

A
L
P
H
A
MOTS-c 10mg
Lab Verified99% PURITY
1 / 4
Molecular Structure
Drag to rotate

MOTS-c 10mg

EliteMetabolic Signaling
4.5(2 reviews)
Lab Certified
99% Pure
Fast Shipping
Analytically Verified
$40.00
🧬

What It Is

MOTS-c (Mitochondrial Open Reading Frame of the Twelve S rRNA type-c) is a 16-amino-acid peptide encoded within the mitochondrial genome — specifically within the 12S rRNA gene. Discovered by Dr. Changhan David Lee at the University of Southern California in 2015, it was the first mitochondrial-derived peptide shown to translocate to the nucleus and directly regulate nuclear gene expression. MOTS-c activates AMPK (AMP-activated protein kinase), the cell's master energy sensor, and modulates the folate-methionine cycle, influencing de novo purine biosynthesis.
🔬

Why Researchers Study It

The discovery that mitochondria — organelles with their own ancient genome — can send peptide signals to the nucleus rewrites our understanding of intracellular communication. Biology encodes a dialogue between two genomes within a single cell: the nuclear genome inherited from both parents, and the mitochondrial genome inherited solely through the maternal line. MOTS-c is a messenger in this conversation — a signal from one genome to another, coordinating the cell's energy economy.

What Makes Ours Different

At 99%+ purity (HPLC verified), our MOTS-c supports research into mitochondrial-nuclear crosstalk, AMPK signaling, and mitochondrial-derived peptide biology.
1
Ships Within 24 Hours
$15 flat rate shipping — Free over $300
99%+ Purity
Lab Certified
Insulated
Free Shipping

RESEARCH USE ONLY: This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease. For laboratory and research purposes only.

Quantum Alpha InsightThe Mitochondrial Messenger

MOTS-c is a mitochondrial-derived peptide — one of the first signaling molecules discovered to be encoded by mitochondrial DNA rather than nuclear DNA. MOTS-c represents a paradigm shift in cellular communication research, with published studies documenting its role in metabolic pathway modulation.

Metabolic Signaling · Elite Cellular Support
Signal Classification
Mitochondrial Messenger
mtDNA-EncodedAMPK ActivationMetabolic Pathway Modulation
~35+ published studies
Quantum Alpha →
Research Philosophy

This compound is offered strictly for laboratory research use. The molecular architecture of each peptide in our catalog reflects remarkable structural complexity — and we believe that studying these structures with the highest quality materials is a matter of scientific integrity, not just regulatory compliance.

All products are intended for laboratory research and analytical purposes only. Not for human consumption.

"Gratitude is not just an emotion — it is a frequency. At 540 MHz, it is one of the highest vibrational states that can be sustained. Cells respond accordingly."

Key Benefits

  • Mitochondrial-Derived Peptide
  • AMPK Activation Research
  • Metabolic Regulation Studies
  • Exercise Mimetic Research
  • Cellular Energy Pathways
The Covenant

The Alpha Standard

Most settle. We don't. Every vial that leaves our lab carries a promise — verified, sealed, uncompromised. In the Quantum Alpha framework, every signal matters.

Purity Is Discipline

99%+ HPLC-verified. Every batch. No exceptions. Because precision isn't optional — it's the standard.

The Narrow Gate

Most settle for 95%. We chose 99%+. The narrow gate isn't easy — but it's the only one worth walking through.

Insulated Shipping Covenant

Insulated packaging. Ships within 24 hours. Free over $300. Your compounds arrive exactly as they should.

Full Transparency

Certificate of Analysis available on request — mass spec, HPLC, and endotoxin data. Nothing hidden.

"The invisible creates the visible. Signal precedes structure. Purity is a frequency. Stay Alpha."

Molecular Visualization

Mitochondrial-Derived Peptide
Key Benefits Visualized
Mitochondrial-Derived PeptideAMPK Activation ResearchMetabolic Regulation Studies+2 more

Abstract molecular visualization of mots-c 10mg benefits

Ingredients

  • MOTS-c 10mg
  • 99%+ Purity (HPLC)
  • Lyophilized Powder

Published Research

Peer-reviewed studies relevant to MOTS-c 10mg. Each reference links directly to PubMed for full-text access.

2 published studies
100% peer-reviewed

"It is the glory of God to conceal a matter; to search out a matter is the glory of kings." — Proverbs 25:2

Researcher Reviews

4.5(2)

Write a Review

Excellent

Please sign in to leave a review

Laura G.Verified Purchase
2/3/2026

Good product for our metabolic peptide research. We're studying MOTS-c alongside NAD+ for our cellular energy pathway work. Both products from Alpha Aminos are consistently high purity.

Jonathan P.Verified Purchase
1/17/2026

MOTS-c is a fascinating mitochondrial-derived peptide to study. The AMPK activation pathway research is compelling. Alpha Aminos provides research-grade quality with proper documentation.

Researcher Reviews — MOTS-c 10mg

Verified lab and research experiences

D
David K.
MOTS-c
8 weeks

"MOTS-c — rare peptide, excellent quality"

MOTS-c is difficult to source from reliable suppliers. Alpha Aminos is one of the few that carries it with proper documentation. Our mitochondrial research lab verified the purity at 98.9% and the amino acid sequence was correct. The 10mg vial was properly lyophilized and sealed. Shipping was fast — 2 days to our facility. The price point is competitive for this particular peptide. We've been ordering for 8 weeks of ongoing research and the quality has been consistent across reorders.

Questions & Answers

Have a question about MOTS-c 10mg?

No questions yet. Be the first to ask!

Quantum Reflections

Weekly scripture + cellular biology insights delivered to your inbox.

Join the Alpha Newsletter

Product updates, research highlights, exclusive discounts, and new catalog alerts. By subscribing, you agree to our Privacy Policy.

Alpha AminosALPHAAMINOS

Premium research-grade peptide compounds. Third-party tested, 99%+ purity verified, laboratory certified. For research and analytical use only.

[email protected]+1 (480) 681-1646
4202 E Elwood St, Phoenix, AZ 85040

IMPORTANT NOTICE — RESEARCH CHEMICALS ONLY: All products sold on this website are strictly for laboratory research, in-vitro testing, and analytical purposes only. These products are not intended for human consumption, therapeutic use, or any application in or on the human body. They have not been evaluated by the Food and Drug Administration (FDA) and are not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you confirm that you are at least 18 years of age and that these products will be used exclusively for legitimate research purposes. Alpha Aminos assumes no liability for misuse of these products.

NOT MEDICAL ADVICE: This website does not provide medical advice. All information, content, and materials available on this site are for general educational and research informational purposes only. Nothing on this website is intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.

CERTIFICATES OF ANALYSIS: Third-party certificates of analysis (COA) are available upon request for all products. Contact [email protected] with your order number and batch reference.

The invisible creates the visible.Signal precedes structure.Precision in every molecule.Separation is an illusion.Purity is a frequency.Every compound is a signal. Every signal has a destination.The research precedes the revelation.Every signal carries information.Honor the architecture of biology.We don't just supply compounds. We supply confidence in your research.Where science meets reverence, discovery follows.Molecular architecture reveals the blueprint of life.The invisible creates the visible.Signal precedes structure.Precision in every molecule.Separation is an illusion.Purity is a frequency.Every compound is a signal. Every signal has a destination.The research precedes the revelation.Every signal carries information.Honor the architecture of biology.We don't just supply compounds. We supply confidence in your research.Where science meets reverence, discovery follows.Molecular architecture reveals the blueprint of life.

© 2026 Alpha Aminos LLC. All rights reserved.

Where Inquiry Meets Molecular Precision

MOTS-c 10mg

$40.00
1

Research Use Only|All products are intended for laboratory research and analytical purposes only. Not for human consumption. Not evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease.

Research Mode
Play 432Hz
Ask me anything!